The main reason for this posting is so I do not lose the paper, “Analysis of radon associated squamous cell carcinomas of the lung for a p53 gene hotspot.”
The World Health Organization went out of its way to prove that active smoking caused lung cancer, (denied by tobacco companies) by inducing a genetic mutation of the p53 gene called a guanine to thymine (G to T) transversion. There are two base pairs that make up our DNA, adenine (A) which forms a base pair with thymine (T) and guanine (G) forms a base pair with cytosine (C).
What happens is that adenine instead of pairing with thymine, it pairs with guanine, (please correct me if I am wrong.) The purpose of the p53 gene is to detect and repair DNA damage and stop the multiplication of cancer cells. Active smoking deactivates the p53 putting it simply. However the WHO also found that this happened “…rarely in lung cancers of non-smokers.”
However this new research I have uncovered suggests that the G to T transversion occurs in non smokers exposed to radon gas. In one Colorado mine 12 out of 41 cases were G to T transversions and 2 out of 38 in Saxony (Stollberg) Germany.
I have missed a portion out here but the anti smoking lobby maybe forced to admit that there has not been one death from lung cancer from passive smoking.